α-CGRP (mouse, rat) SCNTATCVTHRLAGLLSRSGGVVKDNFVPTNVGSEAF-amide
Endogenous calcitonin gene-related peptide receptor (CGRP) agonist which is secreted in both peripheral and central neurons
Catalogue number crb1000889 Molecular Weight 3803.9 Sequence (one letter code) SCNTATCVTHRLAGLLSRSGGVVKDNFVPTNVGSEAF-amide Sequence (three letter code) H-Ser-Cys-Asn-Thr-Ala-Thr-Cys-Val-Thr-His-Arg-Leu-Ala-Gly-Leu-Leu-Ser-Arg-Ser-Gly-Gly-Val-Val-Lys-Asp-Asn-Phe-Val-Pro-Thr-Asn-Val-Gly-Ser-Glu-Ala-Phe-NH2 Aliase a-Calcitonin gene-related peptide (mouse, rat) Modifications Disulfide bridge Cys2 - Cys7 Purity >95% cas 96827-03-1 Storage -20°C References
Nakamura et al (1998) Calcitonin gene-related peptide as a GH secretagogue in human and rat pituitary somatotrophs. Brain Res. 807 203 PMID: 9757038
Poyner (1995) Pharmacology of receptors for calcitonin gene-related peptide and amylin. TiPS 16 424 PMID: 8578616
Salim et al (1998) Calcitonin gene-related peptide potentiates nicotinic acetylcholine receptor-operated slow Ca2+ mobilization at mouse muscle endplates. Br.J.Pharmacol. 125 277 PMID: 9786499
Manufactured in: United Kingdom
Endogenous calcitonin gene-related peptide receptor (CGRP) agonist which is secreted in both peripheral and central neurons. It is a potent vasodilator and can function in the transmission of nociception as well as acting as an appetite suppressant and contributing to gastric acid secretion. It also has a function in temperature homeostasis, increases heart rate, and can play a role in the release of the pituitary hormone.