Calcitonin, Rat CGNLSTCMLGTYTQDLNKFHTFPQTSIGVGAP-amide

  • Description

  • Application Data

Description

The hormone Calcitonin, reduces the amount of serum calcium during hypercalcemia.

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Application Data

Catalogue number crb1001442
Molecular Weight 3397.6
Sequence (one letter code) CGNLSTCMLGTYTQDLNKFHTFPQTSIGVGAP-amide
Sequence (three letter code) H-Cys-Gly-Asn-Leu-Ser-Thr-Cys-Met-Leu-Gly-Thr-Tyr-Thr-Gln-Asp-Leu-Asn-Lys-Phe-His-Thr-Phe-Pro-Gln-Thr-Ser-Ile-Gly-Val-Gly-Ala-Pro-NH2 (Disulfide bridge: Cys1-Cys7)
Modifications Disulfide bridge: Cys1-Cys7
Purity >95%
Storage -20°C
References

Felsenfeld and Levine (2015) Calcitonin, the forgotten hormone: does it deserve to be forgotten. Clin. Kidney J. 8(2): 180 PMID: 25815174

Wimalawansa (2010) Calcitonin: History, Physiology, Pathophysiology and Therapeutic Applications. Osteaoporosis in Men Chapter 53; 653 https://doi.org/10.1016/B978-0-12-374602-3.00053-5

Suzuki (2016) Calcitonin. Handbook of Hormones; Subchapter 27A 232-234 https://doi.org/10.1016/B978-0-12-801028-0.00170-7

Manufactured in: United Kingdom
Data Sheet Material Safety Data Sheet (MSDS)

The hormone Calcitonin, reduces the amount of serum calcium during hypercalcemia and is released from the C-cells of the thyroid gland. Within its structure it contains a disulphide bridge between cysteine 1 and 7 and a proline at its carboxy terminal.

Calcitonin is used therapeutically in the treatment of hypercalcemia diseases such as Paget’s disease, Sudeck’s atrophy, bone metastases and vitamin-D intoxication.

The level of calcitonin in the plasma can also be used as a marker for medullary thyroid carcinoma, while procalcitonin is used to diagnose sepsis.

Calcitonin, Rat

Cat No.Pack SizePriceQty.
0.5mg£170.00
1mg£220.00
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