(Arg8) Vasotocin CYIQNCPRG-amide, disulphide bridge (Cys1-Cys6)


(Arg8) Vasotocin is a neurohypophyseal hormone which as a neuromodulator regulates key physiological processes such as reproduction and sleep.

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Catalogue number crb1000484
Sequence (one letter code) CYIQNCPRG-amide, disulphide bridge (Cys1-Cys6)
Sequence (three letter code) H-Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Arg-Gly-NH2, disulphide bridge (Cys1-Cys6)
Purity >95%
Molecular Weight 1049.5

Usui et al (2005) Characterisation and Distribution of an Arginine Vasotocin Receptor in Mouse. J. Vet. Med. Sci. 68 (7) 655 PMID: 16891776 

(Arg8) Vasotocin (AVT) is a member of the neurohypophyseal hormone family which contains 9 amino acids with the cysteines at positions 1 and 6 linked through a disulphide bridge. Within the central nervous system of lower vertebrates, AVT has been shown to play a role as a neuromodulator and controls reproductive behaviour. Furthermore it regulates osmotic and electrolyte balance and blood pressure within the periphery. In the mammalian brain AVT functions through arginine vasopressin (AVP) or oxytocin receptor cross-reactions. Mice have an AVT reactive receptor specific to AVT and neuropeptide S. This AVT which functions to regulate processes such as sleep and reproduction.

(Arg8) Vasotocin

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