Potent and selective glucagon-like peptide-1 receptor (GLP-1R) antagonist
See full description
Xu et al (2018) Glucagon-Like Peptide-1 Mediates the Protective Effect of the Dipeptidyl Peptidase IV Inhibitor on Renal Fibrosis via Reducing the Phenotypic Conversion of Renal Microvascular Cells in Monocrotaline-Treated Rats. BioMed. Res. Int. 2018 1 PMID: 29607314
Truncated exendin-3 peptide, potent and selective glucagon-like peptide-1 receptor (GLP-1R) antagonist. Exendin-3 shares homology with vasoactive intestinal peptide (VIP), secretin, helospectin I and II and helodermin. Exendin-3 stimulates the increases in cellular cAMP levels and amylase release from pig pancreatic cells.
Exendins are a group of peptide hormones of the glucagon superfamily. Exendins stimulate insulin secretion in response to rising blood glucose levels, and modulate gastric emptying to slow the entry of ingested sugars into the bloodstream. Exendin-3 was originally isolated from the Mexican beaded lizard (Heloderma horridum) venom gland
Search our datasheets by catalogue number, peptide sequence or name.
Discover more about how we can support you and our products.
Find answers to common queries about our products and company.
Cambridge Research Biochemicals 17-18 Belasis Court, Belasis Hall Technology Park Billingham TS23 4AZ
t +44 01642 567 183