Biologically active metabolite of Ang-(1-7) labelled with 13C and 15N stable isotopes
See full description
Yu, L., Yuan, K., Phuong, H., Park, B. and Kim, S. (2016). Angiotensin-(1-5), an active mediator of renin-angiotensin system, stimulates ANP secretion via Mas receptor. Peptides, 86, 33-41. PMID: 27660028
Angiotensin 1-5 (Ang- (1-5)) is a biologically active metabolite of Ang-(1-7). Its production is catalysed by angiotensin-converting enzyme (ACE). Like Ang-(1-7), Ang-(1-5) stimulates atrial natriuretic peptide (ANP) secretion via the G-protein-coupled receptor, Mas.
The valine residue at position 3 and the isoleucine residue at position 5 of this peptide are isotopically labelled with carbon-13 (11) and nitrogen-15 (2), giving this peptide a mass increase of 13 compared to the unlabelled peptide
Search our datasheets by catalogue number, peptide sequence or name.
Discover more about how we can support you and our products.
Find answers to common queries about our products and company.
Cambridge Research Biochemicals 17-18 Belasis Court, Belasis Hall Technology Park Billingham TS23 4AZ
t +44 01642 567 183