Tetanus Toxin P30 (947-967) FNNFTVSFWLRVPKVSASHLE-acid

Description

Tetanus Toxin P30 (947-967) is a protein that is derived from the single-chain polypeptide neurotoxin produced by Clostridium tetani.

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Catalogue number crb1001475
Sequence (one letter code) FNNFTVSFWLRVPKVSASHLE-acid
Sequence (three letter code) H-Phe-Asn-Asn-Phe-Thr-Val-Ser-Phe-Trp-Leu-Arg-Val-Pro-Lys-Val-Ser-Ala-Ser-His-Leu-Glu-OH
Purity >95%
Storage -20°C
Molecular Weight 2477.3
References

Pellizzari et al (1999). Tetanus and botulinum neurotoxins: mechanism of action and therapeutic uses. Philos Trans R Soc Lond B Biol Sci. PMID: 10212474

Surana et al (2018). The travel diaries of tetanus and botulinum neurotoxins. Toxicon. PMID: 29031941

Tetanus Toxin P30 (947-967) is a protein that is derived from the single-chain polypeptide neurotoxin produced by Clostridium tetani. The neurotoxins produced by Clostridium tetani are among the most potent molecules known to humankind. Once in the body, the toxin binds to the basal lamina at the neuromuscular junction. From here, the toxin is transported to inhibitory interneurons in the spinal cord, where it prevents the release of neurotransmitters, which causes spastic paralysis. 

Tetanus Toxin P30 (947-967)

Cat No. Pack Size Price Qty

crb1001475h

0.5mg

$112.50

crb1001475j

1mg

$150.00